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Welcome to the Bioinfotropes Wiki
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Bioinfotropes is a collection of patterns, paradigms, and concepts for guiding new discoveries in systems biology and building better descriptions of familiar systems. Common themes in the evolutionary behavior of systems biology, in the observed behaviors of various bioinformatics tools and approaches, in rationales for rule-based annotation and hypothesis generation, and in emerging descriptive frameworks from the bioinformatics literature are discussed here. The coinage "Bioinfotropes" pays tribute to TV Tropes, a cataloguing of literary devices and conventions that writers can predict will resonate with the expectations and experience of their audiences.
Listed BioinfotropesEdit
Anna Karenina principle for microbiomes
fitness factors a.k.a. lysogenic conversion genes, "morons"
Genome Properties and SEED Subsystems
non-orthologous gene displacement
phylogenetic footprinting (contribution invited)
uniform functional organization
upstream and auxiliary components
History and SupportEdit
Bioinfotropes was founded in November 2010 by Daniel Haft, an Assistant Professor at the J. Craig Venter Institute, as a means to create vocabularies through which experts in bioinformatics can more easily communicate their findings and methods. It is also intended to serve as resource that will enhance community development of rule-based annotation. This project abstracts a number of advances in bioinformatics in which the logic of the approach exploits special characteristics of the class of system under study. Bioinfotropes includes discussions of recent and on-going work supported by grant R01 HG004881 from NIH/NHGRI, but enthusiastically invites all scholarly contributions that fit the open spirit of the project.
Latest activityEdit
- Fitness factors
edited by Daniel haft 4 minutes ago
- Fitness factors
created by Daniel haft 7 minutes agoNew page: Phage (viruses of bacteria) are selfish genetic elements, but the reproductive strategy of lysogenic phage is to integrate into host DNA, repress... Summary: Created page, listed five features. - Bioinfotropes Wiki
edited by Daniel haft 28 minutes ago Summary: added fitness factors link - Misannotation's greatest hits
edited by A Wikia contributor Summary: minor fixes after adding two original sin types of errors. - Misannotation's greatest hits
edited by Daniel haft - Orphan marker
edited by A Wikia contributor - One-gene system
edited by Daniel haft - One-gene system
edited by Daniel haft Summary: Mention that one-gene can make in silico analysis intractable (which is the point of the article) - Verschlimmbessern
created by Daniel haftNew page: Verschlimmbessern is making something worse by a well-meaning but misguided attempt to make it better. It is a common source of error in genome... Summary: New page, with first example. - Protein sorting system
edited by Daniel haft